Biography
I have been at UCSF since 1975 and on the faculty of the Department of Medicine in the division of Nephrology since 1976 and have been involved with the transplant service in patient care and clinical trials with novel immunosuppression drugs
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of California, San Francisco | Residency | School of Medicine |
Board Certifications
American Board of Internal Medicine, Internal Medicine
American Board of Internal Medicine, Nephrology - Subspecialty
Clinical Expertise
Internal Medicine
Transplant Nephrology
Kidney Transplantation
Pancreas Transplantation
Living Kidney Donor Transplantation
End Stage Renal Disease (Kidney Failure)
Chronic Kidney Disease
Clinical Trials
- Related Conditions: End Stage Renal Disease, Kidney Disease| Start Date: | End Date:
- Tocilizumab for Renal Graft Inflammation (NCT02108600)Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: Kidney Transplant, Transplants, Immunotherapy| Start Date: | End Date:
- NFAT-Dependent Cytokine Gene Expression for Immune Monitoring in Kidney Transplant Patients (NCT01771705)Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: Autoimmune Disease, Kidney Transplant| Start Date: | End Date:
- Daratumumab and Belatacept for Desensitization (NCT04827979)Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Treg Modulation With CD28 and IL-6 Receptor Antagonists (NCT04066114)Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Precision Medicine Offers Belatacept Monotherapy (NCT02939365)Related Conditions: Transplants| Start Date: | End Date:
- Letermovir Versus Valganciclovir to Prevent Human Cytomegalovirus Disease in Kidney Transplant Recipients (MK-8228-002) (NCT03443869)Related Conditions: Cytomegalovirus, Human Cytomegalovirus, Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: Kidney Transplant, Transplants, Immunotherapy| Start Date: | End Date:
- Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
In the News
January, 28, 2016 | UCSF Transplant Surgery
August, 27, 2014 | UCSF Transplant Surgery
Grants and Funding
- Applying precision MEdicine to optimize desensitization with noveL bIOlogics or cellular theRApies in highly sensiTized kidney transplant patiEnts (AMELIORATE) | NIH | 2014-07-01 - 2024-05-31 | Role: Principal Investigator
- General Clinical Research Center | NIH | 1974-12-01 - 2009-03-31 | Role: Co-Investigator
Research Interests
Transplant Nephrology
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 276
- The hepatocyte growth factor mimetic, ANG-3777, in kidney transplant recipients with delayed graft function: Results from a randomized phase 3 trial.| | View in PubMed
- Isatuximab Monotherapy for Desensitization in Highly Sensitized Patients Awaiting Kidney Transplant.| | View in PubMed
- State of the art in childhood nephrotic syndrome: concrete discoveries and unmet needs.| | View in PubMed
- Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients: A Randomized Clinical Trial.| | View in PubMed
- Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses.| | View in PubMed
- Open letter to Bristol Myers Squibb: Belatacept; we aren't done yet.| | View in PubMed
- Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study.| | View in PubMed
- Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.| | View in PubMed
- Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses.| | View in PubMed
- Burden of neutropenia and leukopenia among adult kidney transplant recipients: A systematic literature review of observational studies.| | View in PubMed
- Obinutuzumab Effectively Depletes Key B-cell Subsets in Blood and Tissue in End-stage Renal Disease Patients.| | View in PubMed
- Infliximab Induction Lacks Efficacy and Increases BK Virus Infection in Deceased Donor Kidney Transplant Recipients: Results of the CTOT-19 Trial.| | View in PubMed
- Outcomes among CMV-mismatched and highly sensitized kidney transplants recipients who develop neutropenia.| | View in PubMed
- IL-6 and TNFα Drive Extensive Proliferation of Human Tregs Without Compromising Their Lineage Stability or Function.| | View in PubMed
- Conversion from Calcineurin Inhibitor- to Belatacept-Based Maintenance Immunosuppression in Renal Transplant Recipients: A Randomized Phase 3b Trial.| | View in PubMed
- Application of the iBox prognostication system as a surrogate endpoint in the TRANSFORM randomised controlled trial: proof-of-concept study.| | View in PubMed
- Tests for the noninvasive diagnosis of kidney transplant rejection should be evaluated by kidney transplant programs.| | View in PubMed
- A Comparison of Ex Vivo Expanded Human Regulatory T Cells Using Allogeneic Stimulated B Cells or Monocyte-Derived Dendritic Cells.| | View in PubMed
- Interleukin-6 blockade with tocilizumab increases Tregs and reduces T effector cytokines in renal graft inflammation: A randomized controlled trial.| | View in PubMed
- Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation.| | View in PubMed
- Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients.| | View in PubMed
- Phase 3 trial Design of the Hepatocyte Growth Factor Mimetic ANG-3777 in Renal Transplant Recipients With Delayed Graft Function.| | View in PubMed
- The impact of belatacept on the phenotypic heterogeneity of renal T cell-mediated alloimmune response: The critical role of maintenance treatment and inflammatory load.| | View in PubMed
- Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation.| | View in PubMed
- A urine score for noninvasive accurate diagnosis and prediction of kidney transplant rejection.| | View in PubMed
- Further Evidence That the Soluble Urokinase Plasminogen Activator Receptor Does Not Directly Injure Mice or Human Podocytes.| | View in PubMed
- Assessment of 19 Genes and Validation of CRM Gene Panel for Quantitative Transcriptional Analysis of Molecular Rejection and Inflammation in Archival Kidney Transplant Biopsies.| | View in PubMed
- A randomized, phase 1b study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of bleselumab, a fully human, anti-CD40 monoclonal antibody, in kidney transplantation.| | View in PubMed
- Evidence-based practice: Guidance for using everolimus in combination with low-exposure calcineurin inhibitors as initial immunosuppression in kidney transplant patients.| | View in PubMed
- Safety, pharmacokinetics, and pharmacodynamic activity of obinutuzumab, a type 2 anti-CD20 monoclonal antibody for the desensitization of candidates for renal transplant.| | View in PubMed
- Two-year outcomes in de novo renal transplant recipients receiving everolimus-facilitated calcineurin inhibitor reduction regimen from the TRANSFORM study.| | View in PubMed
- Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing.| | View in PubMed
- Identifying a potential biomarker for primary focal segmental glomerulosclerosis and its association with recurrence after transplantation.| | View in PubMed
- Efficacy and Safety of a Tofacitinib-based Immunosuppressive Regimen After Kidney Transplantation: Results From a Long-term Extension Trial.| | View in PubMed
- Nuclear Factor of Activated T Cell-regulated Cytokine Gene Expression for Adjustment of Tacrolimus in Kidney Transplant Recipients: A Randomized Controlled Pilot Trial.| | View in PubMed
- A randomized, phase 2 study of ASP0113, a DNA-based vaccine, for the prevention of CMV in CMV-seronegative kidney transplant recipients receiving a kidney from a CMV-seropositive donor.| | View in PubMed
- Everolimus with Reduced Calcineurin Inhibitor Exposure in Renal Transplantation.| | View in PubMed
- Outcomes at 7 years post-transplant in black vs nonblack kidney transplant recipients administered belatacept or cyclosporine in BENEFIT and BENEFIT-EXT.| | View in PubMed
- Targeted Transcriptional Profiling of Kidney Transplant Biopsies.| | View in PubMed
- Mycophenolate Mofetil Withdrawal With Conversion to Everolimus to Treat BK Virus Infection in Kidney Transplant Recipients.| | View in PubMed
- Ten-year outcomes in a randomized phase II study of kidney transplant recipients administered belatacept 4-weekly or 8-weekly.| | View in PubMed
- Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants.| | View in PubMed
- Retrospective evaluation of the efficacy and safety of belatacept with thymoglobulin induction and maintenance everolimus: A single-center clinical experience.| | View in PubMed
- Transplant trials with Tregs: perils and promises.| | View in PubMed
- B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function.| | View in PubMed
- A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis.| | View in PubMed
- Belatacept: the challenges with transformational drugs.| | View in PubMed
- Early post-transplant conversion from tacrolimus to belatacept for prolonged delayed graft function improves renal function in kidney transplant recipients.| | View in PubMed
- Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial.| | View in PubMed
- Current status of costimulatory blockade in renal transplantation.| | View in PubMed
- Costimulatory Blockade and Use of mTOR Inhibitors: Avoiding Injury Part 2.| | View in PubMed
- Steroid-Responsive Acute Rejection Should Not Be the End Point for Immunosuppressive Trials.| | View in PubMed
- Belatacept and Long-Term Outcomes in Kidney Transplantation.| | View in PubMed
- An Update on Calcineurin Inhibitor-Free Regimens: The Need Persists, but the Landscape has Changed.| | View in PubMed
- Belatacept and Long-Term Outcomes in Kidney Transplantation.| | View in PubMed
- A Prospective Cohort Study of Mineral Metabolism After Kidney Transplantation.| | View in PubMed
- A Computational Gene Expression Score for Predicting Immune Injury in Renal Allografts.| | View in PubMed
- Evaluation of the effect of tofacitinib exposure on outcomes in kidney transplant patients.| | View in PubMed
- The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study.| | View in PubMed
- Role of podocyte B7-1 in diabetic nephropathy.| | View in PubMed
- Clinical aspects: focusing on key unique organ-specific issues of renal transplantation.| | View in PubMed
- Long-term belatacept exposure maintains efficacy and safety at 5 years: results from the long-term extension of the BENEFIT study.| | View in PubMed
- Tofacitinib in kidney transplantation.| | View in PubMed
- Report of the second joint meeting of ESOT and AST: current pipelines in biotech and pharma.| | View in PubMed
- Native renal function after combined liver-kidney transplant for type 1 hepatorenal syndrome: initial report on the use of postoperative Technetium-99 m-mercaptoacetyltriglycine scans.| | View in PubMed
- Ciprofloxacin prophylaxis in kidney transplant recipients reduces BK virus infection at 3 months but not at 1 year.| | View in PubMed
- Belatacept in kidney transplantation.| | View in PubMed
- Polyomavirus BK replication in de novo kidney transplant patients receiving tacrolimus or cyclosporine: a prospective, randomized, multicenter study.| | View in PubMed
- Belatacept for prevention of acute rejection in adult patients who have had a kidney transplant: an update.| | View in PubMed
- Altered balance between effector T cells and FOXP3+ HELIOS+ regulatory T cells after thymoglobulin induction in kidney transplant recipients.| | View in PubMed
- Improvement in renal function in kidney transplant recipients switched from cyclosporine or tacrolimus to belatacept: 2-year results from the long-term extension of a phase II study.| | View in PubMed
- Randomized phase 2b trial of tofacitinib (CP-690,550) in de novo kidney transplant patients: efficacy, renal function and safety at 1 year.| | View in PubMed
- Are calcineurin inhibitors-free regimens ready for prime time?| | View in PubMed
- Beyond belatacept: praise and progress for the FDA.| | View in PubMed
- Targeting JAK3 in kidney transplantation: current status and future options.| | View in PubMed
- C4d/CD34 double-immunofluorescence staining of renal allograft biopsies for assessing peritubular capillary C4d positivity.| | View in PubMed
- Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients.| | View in PubMed
- Belatacept-versus cyclosporine-based immunosuppression in renal transplant recipients with pre-existing diabetes.| | View in PubMed
- Belatacept.| | View in PubMed
- Challenges and opportunities in targeting the costimulation pathway in solid organ transplantation.| | View in PubMed
- Novel strategies in immunosuppression: issues in perspective.| | View in PubMed
- Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies).| | View in PubMed
- Sotrastaurin, a novel small molecule inhibiting protein-kinase C: randomized phase II study in renal transplant recipients.| | View in PubMed
- A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis.| | View in PubMed
- Response to questions regarding the design and results of the IMPACT trial.| | View in PubMed
- An integrated safety profile analysis of belatacept in kidney transplant recipients.| | View in PubMed
- Belatacept-based regimens versus a cyclosporine A-based regimen in kidney transplant recipients: 2-year results from the BENEFIT and BENEFIT-EXT studies.| | View in PubMed
- Extended valganciclovir prophylaxis in D+/R- kidney transplant recipients is associated with long-term reduction in cytomegalovirus disease: two-year results of the IMPACT study.| | View in PubMed
- Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade.| | View in PubMed
- How the development of new biological agents may help minimize immunosuppression in kidney transplantation: the impact of belatacept.| | View in PubMed
- Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients.| | View in PubMed
- Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study.| | View in PubMed
- Associations of pretransplant diabetes mellitus, new-onset diabetes after transplant, and acute rejection with transplant outcomes: an analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) database.| | View in PubMed
- Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.| | View in PubMed
- Five-year safety and efficacy of belatacept in renal transplantation.| | View in PubMed
- The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients.| | View in PubMed
- A phase III study of belatacept versus cyclosporine in kidney transplants from extended criteria donors (BENEFIT-EXT study).| | View in PubMed
- A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).| | View in PubMed
- Kidney transplantation at UCSF: 8,300 transplants and onward.| | View in PubMed
- Novel B cell therapeutic targets in transplantation and immune-mediated glomerular diseases.| | View in PubMed
- KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary.| | View in PubMed
- Calcineurin-inhibitor-free immunosuppression based on the JAK inhibitor CP-690,550: a pilot study in de novo kidney allograft recipients.| | View in PubMed
- Kidney transplantation: the ideal immunosuppression regimen.| | View in PubMed
- Transplantation: To convert or not to convert: lessons from the CONVERT trial.| | View in PubMed
- The AST's perspective on the proposed kidney allocation system.| | View in PubMed
- The challenge of achieving target drug concentrations in clinical trials: experience from the Symphony study.| | View in PubMed
- Long-term renal function and cardiovascular disease risk in obese kidney donors.| | View in PubMed
- Evolving trends in induction therapy.| | View in PubMed
- Assessment of belatacept-mediated costimulation blockade through evaluation of CD80/86-receptor saturation.| | View in PubMed
- Mycophenolic acid exposure after administration of mycophenolate mofetil in the presence and absence of cyclosporin in renal transplant recipients.| | View in PubMed
- The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation.| | View in PubMed
- What's next in the pipeline.| | View in PubMed
- Tolerance versus immunosuppression: a perspective.| | View in PubMed
- Association of four DNA polymorphisms with acute rejection after kidney transplantation.| | View in PubMed
- Open letter to the FDA: new drug trials must be relevant.| | View in PubMed
- A randomized, multicenter study of steroid avoidance, early steroid withdrawal or standard steroid therapy in kidney transplant recipients.| | View in PubMed
- Costimulation blockade in autoimmunity and transplantation.| | View in PubMed
- Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: The CAESAR Study. Am J Transplant 7, 560-570, 2007.| | View in PubMed
- Proteomics of plasma and urine in primary nephrotic syndrome in children.| | View in PubMed
- Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus. Am J Transplant 7 1506-1514, 2007.| | View in PubMed
- Rituximab failed to improve nephrotic syndrome in renal transplant patients with recurrent focal segmental glomerulosclerosis.| | View in PubMed
- A phase I/II randomized open-label multicenter trial of efalizumab, a humanized anti-CD11a, anti-LFA-1 in renal transplantation.| | View in PubMed
- Novel immunosuppression: small molecules and biologics.| | View in PubMed
- Pharmacokinetics, safety, and efficacy of mycophenolate mofetil in combination with sirolimus or ciclosporin in renal transplant patients.| | View in PubMed
- Costimulation blockade--what will the future bring?| | View in PubMed
- Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus.| | View in PubMed
- Sirolimus: defining nephrotoxicity in the renal transplant recipient.| | View in PubMed
- Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin.| | View in PubMed
- Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: the CAESAR Study.| | View in PubMed
- T cell costimulation: a rational target in the therapeutic armamentarium for autoimmune diseases and transplantation.| | View in PubMed
- Therapeutic drug monitoring of mycophenolic acid in solid organ transplant patients treated with mycophenolate mofetil: review of the literature.| | View in PubMed
- Living donor kidney transplant recipients and clinical trials: participation profiles and impact on post-transplant care.| | View in PubMed
- Immunosuppression: today, tomorrow, and withdrawal.| | View in PubMed
- Interleukin-2 receptor antagonist induction in modern immunosuppression regimens for renal transplant recipients.| | View in PubMed
- Antibodies come back to the forefront in transplantation.| | View in PubMed
- A multicenter, prospective study of C2-monitored cyclosporine microemulsion in a U.S. population of de novo renal transplant recipients.| | View in PubMed
- Toxicity-sparing protocols using mycophenolate mofetil in renal transplantation.| | View in PubMed
- Current use and future trends in induction therapy.| | View in PubMed
- Rapidly developing nephrocalcinosis in a patient with end-stage liver disease who received a domino liver transplant from a patient with known congenital oxalosis.| | View in PubMed
- Costimulation blockade with belatacept in renal transplantation.| | View in PubMed
- A drug of the past, a lesson for the future.| | View in PubMed
- Guidelines for the treatment and management of new-onset diabetes after transplantation.| | View in PubMed
- New insights into the pathogenesis and the therapy of recurrent focal glomerulosclerosis.| | View in PubMed
- Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation.| | View in PubMed
- An open-label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency.| | View in PubMed
- Rationale and design of the DIRECT study: a comparative assessment of the hyperglycemic effects of tacrolimus and cyclosporine following renal transplantation.| | View in PubMed
- A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus.| | View in PubMed
- Chronic induction. What's new in the pipeline.| | View in PubMed
- BK nephropathy in kidney transplant recipients treated with a calcineurin inhibitor-free immunosuppression regimen.| | View in PubMed
- Interleukin-2 receptor antagonists and aggressive steroid minimization strategies for kidney transplant patients.| | View in PubMed
- Infliximab in the treatment of steroid-dependent ulcerative colitis.| | View in PubMed
- A decade of progress in kidney transplantation.| | View in PubMed
- Recurrent focal glomerulosclerosis in the era of genetics of podocyte proteins: theory and therapy.| | View in PubMed
- Optimizing the use of cyclosporine (Neoral) for recipients of living donor kidneys.| | View in PubMed
- Retransplantation in patients with graft loss caused by polyoma virus nephropathy.| | View in PubMed
- Pharmacokinetics of daclizumab and mycophenolate mofetil with cyclosporine and steroids in renal transplantation.| | View in PubMed
- CD69 expression on peripheral CD8 T cells correlates with acute rejection in renal transplant recipients.| | View in PubMed
- Immunosuppression minimization: current and future trends in transplant immunosuppression.| | View in PubMed
- Prevalence and management of anemia in renal transplant recipients: a European survey.| | View in PubMed
- De novo use of sirolimus in immunosuppression regimens in kidney and kidney-pancreas transplantation at the University of California, San Francisco.| | View in PubMed
- Multicenter randomized prospective trial of steroid withdrawal in renal transplant recipients receiving basiliximab, cyclosporine microemulsion and mycophenolate mofetil.| | View in PubMed
- New monoclonal antibodies in renal transplantation.| | View in PubMed
- Pharmacokinetic and pharmacodynamic studies of one or two doses of daclizumab in renal transplantation.| | View in PubMed
- What's in the pipeline? New immunosuppressive drugs in transplantation.| | View in PubMed
- A long-term comparison of tacrolimus (FK506) and cyclosporine in kidney transplantation: evidence for improved allograft survival at five years.| | View in PubMed
- Effect of calcineurin inhibitor therapy on P-gp expression and function in lymphocytes of renal transplant patients: a preliminary evaluation.| | View in PubMed
- Interleukin-2 receptor monoclonal antibodies in renal transplantation: current use and emerging regimens.| | View in PubMed
- Daclizumab (humanized anti-IL2Ralpha mAb) prophylaxis for prevention of acute rejection in renal transplant recipients with delayed graft function.| | View in PubMed
- Rapid steroid withdrawal versus standard steroid therapy in patients treated with basiliximab, cyclosporine, and mycophenolate mofetil for the prevention of acute rejection in renal transplantation.| | View in PubMed
- Tacrolimus (FK 506) in kidney transplantation: five-year survival results of the U.S. multicenter, randomized, comparative trial.| | View in PubMed
- The role of newer monoclonal antibodies in renal transplantation.| | View in PubMed
- Phase I trial of HuM291, a humanized anti-CD3 antibody, in patients receiving renal allografts from living donors.| | View in PubMed
- A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.| | View in PubMed
- Coadministration of tacrolimus and mycophenolate mofetil in stable kidney transplant patients: pharmacokinetics and tolerability.| | View in PubMed
- The role of daclizumab in balancing resources for inpatient and outpatient transplant services.| | View in PubMed
- Daclizumab prevents acute rejection and improves patient survival post transplantation: 1 year pooled analysis.| | View in PubMed
- Recurrent and de novo glomerular disease after renal transplantation: a report from Renal Allograft Disease Registry (RADR).| | View in PubMed
- Daclizumab: novel biologic immunoprophylaxis for prevention of acute rejection in renal transplantation.| | View in PubMed
- Potential of daclizumab in solid organ transplantation.| | View in PubMed
- Can antibody prophylaxis allow sparing of other immunosuppressives?| | View in PubMed
- Recurrent and de novo glomerular disease after renal transplantation: a report from renal allograft disease registry.| | View in PubMed
- Review of transplantation--1999.| | View in PubMed
- Histopathologic findings from 2-year protocol biopsies from a U.S. multicenter kidney transplant trial comparing tarolimus versus cyclosporine: a report of the FK506 Kidney Transplant Study Group.| | View in PubMed
- Daclizumab: outcome of phase III trials and mechanism of action. Double Therapy and the Triple Therapy Study Groups.| | View in PubMed
- Single-center long-term results of renal transplantation for IgA nephropathy.| | View in PubMed
- Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation. Daclizumab Triple Therapy Study Group.| | View in PubMed
- Selection strategies for successful utilization of less than 15.kg pediatric donor kidneys.| | View in PubMed
- A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression after cadaveric renal transplantation. FK506 Kidney Transplant Study Group.| | View in PubMed
- FK 506 in kidney transplantation: results of the U.S.A. randomized comparative phase III study. The FK 506 Kidney Transplant Study Group.| | View in PubMed
- Immunologic and patient selection strategies for successful utilization of less than 15 kg pediatric donor kidneys--long term experiences with 40 transplants.| | View in PubMed
- A phase I trial of humanized anti-interleukin 2 receptor antibody in renal transplantation.| | View in PubMed
- An open-label, concentration-ranging trial of FK506 in primary kidney transplantation: a report of the United States Multicenter FK506 Kidney Transplant Group.| | View in PubMed
- A multicenter trial of FK506 (tacrolimus) therapy in refractory acute renal allograft rejection. A report of the Tacrolimus Kidney Transplantation Rescue Study Group.| | View in PubMed
- One-year follow-up of an open-label trial of FK506 for primary kidney transplantation. A report of the U.S. Multicenter FK506 Kidney Transplant Group.| | View in PubMed
- Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis.| | View in PubMed
- In vivo (phase I) trial and in vitro efficacy of humanized anti-Tac for the prevention of rejection in renal transplant recipients.| | View in PubMed
- Pentoxifylline does not prevent the cytokine-induced first dose reaction following OKT3--a randomized, double-blind placebo-controlled study.| | View in PubMed
- Fibrosing cholestatic hepatitis in renal transplant recipients.| | View in PubMed
- Histopathological concordance of paired renal allograft biopsy cores. Effect on the diagnosis and management of acute rejection.| | View in PubMed
- Long-term outcome in kidney transplant patients with hepatitis C (HCV) infection.| | View in PubMed
- Phase II FK 506 multicenter concentration control study: one-year follow-up.| | View in PubMed
- The risk of transmission of hepatitis B from HBsAg(-), HBcAb(+), HBIgM(-) organ donors.| | View in PubMed
- Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis.| | View in PubMed
- Pentoxifylline reduces the first-dose reactions following OKT3.| | View in PubMed
- Nontransmission of hepatitis C from cadaver kidney donors to transplant recipients.| | View in PubMed
- Hepatitis C--its prevalence in end-stage renal failure patients and clinical course after kidney transplantation.| | View in PubMed
- Recurrent focal glomerulosclerosis: natural history and response to therapy.| | View in PubMed
- Cytokine and T cell receptor gene expression at the site of allograft rejection.| | View in PubMed
- Hepatitis C virus in cadaver organ donors: prevalence and risk of transmission to transplant recipients.| | View in PubMed
- Effect of cyclosporine on the clinical course of HBsAg-positive renal transplant patients.| | View in PubMed
- Improved results with combined donor-specific transfusion (DST) and sequential therapy protocol.| | View in PubMed
- Inability of cyclosporine to completely prevent the recurrence of focal glomerulosclerosis after kidney transplantation.| | View in PubMed
- Immunologic alterations induced by donor-specific transfusion.| | View in PubMed
- Successful management of the highly sensitized renal allograft recipient.| | View in PubMed
- The incidence and impact of herpes simplex virus infections in the first month following renal transplantation.| | View in PubMed
- Cyclosporine provides better success rates for both higher- and lower-risk cadaveric kidney transplant recipients.| | View in PubMed
- How to improve results for second renal allografts.| | View in PubMed
- Is cyclosporine effective in preventing recurrence of immune-mediated glomerular disease after renal transplantation?| | View in PubMed
- Posttransplant renal rejection: comparison of quantitative scintigraphy, US, and MR imaging.| | View in PubMed
- Donor-specific blood transfusions versus cyclosporine--the DST story.| | View in PubMed
- Has cyclosporine really relegated pretransplant blood transfusions to therapeutic obsolescence?| | View in PubMed
- Observations relating to the incidence of the acquired immune deficiency syndrome and other possibly associated conditions in a large population of renal transplant recipients.| | View in PubMed
- Sonography in the diagnosis of acute renal allograft rejection and cyclosporine nephrotoxicity.| | View in PubMed
- The beneficial effect of pretransplant blood transfusions in cyclosporine-treated cadaver renal allograft recipients.| | View in PubMed
- Renal allograft rejection: US evaluation.| | View in PubMed
- The clinical course of IgA-nephropathy and Henoch-Schönlein purpura following renal transplantation.| | View in PubMed
- Clinical management of immunosuppressive therapy for cyclosporine-treated recipients of cadaver kidney transplants at one to six months.| | View in PubMed
- Is a "low" dose of prednisone better than a "high" dose at the time of renal transplantation?| | View in PubMed
- A seven-year experience with donor-specific blood transfusions. Results and considerations for maximum efficacy.| | View in PubMed
- Pharmacokinetics of sulfisoxazole in renal transplant patients.| | View in PubMed
- Dramatic improvement in the success rate for renal transplants in diabetic recipients with donor-specific transfusions.| | View in PubMed
- Peptic ulcer disease in kidney transplant recipients.| | View in PubMed
- Parathyroid and bone response of the diabetic patient to uremia.| | View in PubMed
- Long-term renal function in kidney donors. Sustained compensatory hyperfiltration with no adverse effects.| | View in PubMed
- The role of blood transfusions in renal transplantation.| | View in PubMed
- De novo and recurrent membranous glomerulopathy following kidney transplantation.| | View in PubMed
- Furosemide assays and disposition in healthy volunteers and renal transplant patients.| | View in PubMed
- Urinary kallikrein excretion after renal transplantation: relationship to hypertension, graft source, and renal function.| | View in PubMed
- Blood transfusions before and on the day of transplantation: effects on cadaver graft survival.| | View in PubMed
- Update of the University of California at San Francisco experience with donor-specific blood transfusions.| | View in PubMed
- Blood transfusions and kidney transplantation.| | View in PubMed
- Prednisone and prednisolone bioavailability in renal transplant patients.| | View in PubMed
- Prognostic features of early renal transplant rejections.| | View in PubMed
- Septic arthritis following renal transplantation.| | View in PubMed
- An alternative to cadaver kidney transplants for patients with insulin-dependent diabetes mellitus.| | View in PubMed
- Incidence, characteristics, and outcome of recipients sensitized after donor-specific blood transfusions.| | View in PubMed
- Improved graft survival following donor-specific blood transfusions.| | View in PubMed
- Prevention of prednisone-induced negative nitrogen balance. Effect of dietary modification on urea generation rate in patients on hemodialysis receiving high-dose glucocorticoids.| | View in PubMed
- 1,500 renal transplants at one center: evolution of a strategy for optimal success.| | View in PubMed
- Furosemide kinetics and dynamics after kidney transplant.| | View in PubMed
- Recurrent systemic lupus erythematosus involving renal allografts.| | View in PubMed
- Decreased secondary hyperparathyroidism in diabetic patients receiving hemodialysis.| | View in PubMed
- Graft survival with high levels of cytotoxic antibodies.| | View in PubMed
- Improved graft survival with donor-specific transfusion pretreatment.| | View in PubMed
- Pretreatment with donor-specific blood transfusions in related recipients with high MLC.| | View in PubMed
- Prednisolone disposition in cushingoid and noncushingoid kidney transplant patients.| | View in PubMed
- Improved outcome following renal transplantation with reduction in the immunosuppression therapy for rejection episodes.| | View in PubMed
- The role of hypertension in hemodialysis-associated atherosclerosis.| | View in PubMed
- Post-transplantation pyelonephritis: factors producing low patient and transplant morbidity.| | View in PubMed
- Deliberate donor-specific blood transfusions prior to living related renal transplantation. A new approach.| | View in PubMed
- The organization of a successful donor-specific transfusion protocol in related recipients with high MLC.| | View in PubMed
- Donor-specific blood transfusions in HLA-D-disparate one-haplotype-related allografts.| | View in PubMed
- Results and significance of angiography in potential kidney donors.| | View in PubMed
- The transplanted kidney as a source of hepatitis B infection.| | View in PubMed
- Analysis of costs and outcomes of renal transplantation at one center. Its implications.| | View in PubMed
- Comparative study of albumin solution and cryoprecipitated plasma for renal preservation: a preliminary report.| | View in PubMed
- HLA-D antigen disparity and HLA-DRw antibodies in intrafamilial renal allograft survival.| | View in PubMed
- The influence of donor age on graft survival.| | View in PubMed
- Do blood transfusions enhance the possibility of a compatible transplant?| | View in PubMed
- Pretransplant cytotoxic antibodies do not segregate kidney transplant recipients into responder and non-responder groups.| | View in PubMed
- Immunologic factors determining survival of cadaver-kidney transplants. The effect of HLA serotyping, cytotoxic antibodies and blood transfusions on graft survival.| | View in PubMed
- Leukocyte migration inhibitory factor (LIF) as an indicator of presensitization and allograft survival.| | View in PubMed
- The effect of hypothermic pulsatile perfusion on glomerular epithelial surface structures studied by scanning electron microscopy.| | View in PubMed
- Hepatitis-B reactivation after renal transplantation.| | View in PubMed
- Renal vein renin in hypertension. Diagnostic and therapeutic implications.| | View in PubMed
- Tumorous hyperparathyroidism in hypophosphatemic vitamin D--resistant rickets.| | View in PubMed