Biography
I have been at UCSF since 1975 and on the faculty of the Department of Medicine  in the division of Nephrology  since 1976 and have been involved with the transplant service in patient care and clinical trials with novel immunosuppression drugs
Education
| Institution | Degree | Dept or School | End Date | 
|---|---|---|---|
| University of California, San Francisco | Residency | School of Medicine | 
Board Certifications
American Board of Internal Medicine, Internal Medicine
American Board of Internal Medicine, Nephrology - Subspecialty
Clinical Expertise
Internal Medicine
Transplant Nephrology
Kidney Transplantation
Pancreas Transplantation
Living Kidney Donor Transplantation
End Stage Renal Disease (Kidney Failure)
Chronic Kidney Disease
Clinical Trials
- Daratumumab and Belatacept for Desensitization (NCT04827979)Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- A Study of TCD601 in de Novo Renal Transplant Recipients (NCT05669001)Related Conditions: Kidney Transplant| Start Date: | End Date:
- Treg Modulation With CD28 and IL-6 Receptor Antagonists (NCT04066114)Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Precision Medicine Offers Belatacept Monotherapy (NCT02939365)Related Conditions: Transplants| Start Date: | End Date:
- Tocilizumab for Renal Graft Inflammation (NCT02108600)Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: End Stage Renal Disease, Kidney Disease| Start Date: | End Date:
- NFAT-Dependent Cytokine Gene Expression for Immune Monitoring in Kidney Transplant Patients (NCT01771705)Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: Kidney Transplant, Transplants, Immunotherapy| Start Date: | End Date:
- Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
- Related Conditions: Autoimmune Disease, Kidney Transplant| Start Date: | End Date:
In the News
January, 28, 2016 | UCSF Transplant Surgery
    August, 27, 2014 | UCSF Transplant Surgery
    Grants and Funding
- Applying precision MEdicine to optimize desensitization with noveL bIOlogics or cellular theRApies in highly sensiTized kidney transplant patiEnts (AMELIORATE) | NIH | 2014-07-01 - 2024-05-31 | Role: Principal Investigator
- General Clinical Research Center | NIH | 1974-12-01 - 2009-03-31 | Role: Co-Investigator
Research Interests
Transplant Nephrology
Publications
      MOST RECENT PUBLICATIONS FROM A TOTAL OF 290
    
      
      - Dysregulated Bone Marrow Contributes to Glomerular Injury through Soluble Factors.| | PubMed PubMed
- Clinical events and healthcare resource utilization associated with neutropenia and leukopenia among adult kidney transplant recipients receiving valganciclovir.| | PubMed PubMed
- Healthcare resource use and clinical events associated with neutropenia among adult kidney transplant recipients receiving valganciclovir or ganciclovir prophylaxis: a matched case-control cohort study.| | PubMed PubMed
- Antiplasma cell antibodies: A new era of human leukocyte antigen antibody control in solid organ transplantation.| | PubMed PubMed
- Anti-HLA serologic response to CD38-targeting desensitization therapy is challenged by peripheral memory B cells in highly sensitized kidney transplant candidates.| | PubMed PubMed
- Poised for Innovation: Considerations for End Points for New Drug Development in Kidney Transplantation.| | PubMed PubMed
- Long-term Safety in Epstein-Barr Virus-Seropositive Kidney-only Transplant Recipients Treated With Belatacept in Clinical Practice: Final Study Results From the ENLiST Registry.| | PubMed PubMed
- The hepatocyte growth factor mimetic, ANG-3777, in kidney transplant recipients with delayed graft function: Results from a randomized phase 3 trial.| | PubMed PubMed
- Isatuximab Monotherapy for Desensitization in Highly Sensitized Patients Awaiting Kidney Transplant.| | PubMed PubMed
- State of the art in childhood nephrotic syndrome: concrete discoveries and unmet needs.| | PubMed PubMed
- Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients: A Randomized Clinical Trial.| | PubMed PubMed
- Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses.| | PubMed PubMed
- Open letter to Bristol Myers Squibb: Belatacept; we aren't done yet.| | PubMed PubMed
- Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study.| | PubMed PubMed
- Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.| | PubMed PubMed
- Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses.| | PubMed PubMed
- Burden of neutropenia and leukopenia among adult kidney transplant recipients: A systematic literature review of observational studies.| | PubMed PubMed
- Obinutuzumab Effectively Depletes Key B-cell Subsets in Blood and Tissue in End-stage Renal Disease Patients.| | PubMed PubMed
- Infliximab Induction Lacks Efficacy and Increases BK Virus Infection in Deceased Donor Kidney Transplant Recipients: Results of the CTOT-19 Trial.| | PubMed PubMed
- Outcomes among CMV-mismatched and highly sensitized kidney transplants recipients who develop neutropenia.| | PubMed PubMed
- IL-6 and TNFα Drive Extensive Proliferation of Human Tregs Without Compromising Their Lineage Stability or Function.| | PubMed PubMed
- Conversion from Calcineurin Inhibitor- to Belatacept-Based Maintenance Immunosuppression in Renal Transplant Recipients: A Randomized Phase 3b Trial.| | PubMed PubMed
- Application of the iBox prognostication system as a surrogate endpoint in the TRANSFORM randomised controlled trial: proof-of-concept study.| | PubMed PubMed
- Tests for the noninvasive diagnosis of kidney transplant rejection should be evaluated by kidney transplant programs.| | PubMed PubMed
- A Comparison of Ex Vivo Expanded Human Regulatory T Cells Using Allogeneic Stimulated B Cells or Monocyte-Derived Dendritic Cells.| | PubMed PubMed
- Interleukin-6 blockade with tocilizumab increases Tregs and reduces T effector cytokines in renal graft inflammation: A randomized controlled trial.| | PubMed PubMed
- Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation.| | PubMed PubMed
- Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients.| | PubMed PubMed
- Phase 3 trial Design of the Hepatocyte Growth Factor Mimetic ANG-3777 in Renal Transplant Recipients With Delayed Graft Function.| | PubMed PubMed
- The impact of belatacept on the phenotypic heterogeneity of renal T cell-mediated alloimmune response: The critical role of maintenance treatment and inflammatory load.| | PubMed PubMed
- Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation.| | PubMed PubMed
- A urine score for noninvasive accurate diagnosis and prediction of kidney transplant rejection.| | PubMed PubMed
- Further Evidence That the Soluble Urokinase Plasminogen Activator Receptor Does Not Directly Injure Mice or Human Podocytes.| | PubMed PubMed
- Assessment of 19 Genes and Validation of CRM Gene Panel for Quantitative Transcriptional Analysis of Molecular Rejection and Inflammation in Archival Kidney Transplant Biopsies.| | PubMed PubMed
- A randomized, phase 1b study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of bleselumab, a fully human, anti-CD40 monoclonal antibody, in kidney transplantation.| | PubMed PubMed
- Evidence-based practice: Guidance for using everolimus in combination with low-exposure calcineurin inhibitors as initial immunosuppression in kidney transplant patients.| | PubMed PubMed
- Safety, pharmacokinetics, and pharmacodynamic activity of obinutuzumab, a type 2 anti-CD20 monoclonal antibody for the desensitization of candidates for renal transplant.| | PubMed PubMed
- Two-year outcomes in de novo renal transplant recipients receiving everolimus-facilitated calcineurin inhibitor reduction regimen from the TRANSFORM study.| | PubMed PubMed
- Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing.| | PubMed PubMed
- Identifying a potential biomarker for primary focal segmental glomerulosclerosis and its association with recurrence after transplantation.| | PubMed PubMed
- Efficacy and Safety of a Tofacitinib-based Immunosuppressive Regimen After Kidney Transplantation: Results From a Long-term Extension Trial.| | PubMed PubMed
- Nuclear Factor of Activated T Cell-regulated Cytokine Gene Expression for Adjustment of Tacrolimus in Kidney Transplant Recipients: A Randomized Controlled Pilot Trial.| | PubMed PubMed
- A randomized, phase 2 study of ASP0113, a DNA-based vaccine, for the prevention of CMV in CMV-seronegative kidney transplant recipients receiving a kidney from a CMV-seropositive donor.| | PubMed PubMed
- Everolimus with Reduced Calcineurin Inhibitor Exposure in Renal Transplantation.| | PubMed PubMed
- Outcomes at 7 years post-transplant in black vs nonblack kidney transplant recipients administered belatacept or cyclosporine in BENEFIT and BENEFIT-EXT.| | PubMed PubMed
- Targeted Transcriptional Profiling of Kidney Transplant Biopsies.| | PubMed PubMed
- Mycophenolate Mofetil Withdrawal With Conversion to Everolimus to Treat BK Virus Infection in Kidney Transplant Recipients.| | PubMed PubMed
- Ten-year outcomes in a randomized phase II study of kidney transplant recipients administered belatacept 4-weekly or 8-weekly.| | PubMed PubMed
- Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants.| | PubMed PubMed
- Retrospective evaluation of the efficacy and safety of belatacept with thymoglobulin induction and maintenance everolimus: A single-center clinical experience.| | PubMed PubMed
- Transplant trials with Tregs: perils and promises.| | PubMed PubMed
- B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function.| | PubMed PubMed
- A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis.| | PubMed PubMed
- Belatacept: the challenges with transformational drugs.| | PubMed PubMed
- Early post-transplant conversion from tacrolimus to belatacept for prolonged delayed graft function improves renal function in kidney transplant recipients.| | PubMed PubMed
- Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial.| | PubMed PubMed
- Current status of costimulatory blockade in renal transplantation.| | PubMed PubMed
- Costimulatory Blockade and Use of mTOR Inhibitors: Avoiding Injury Part 2.| | PubMed PubMed
- Steroid-Responsive Acute Rejection Should Not Be the End Point for Immunosuppressive Trials.| | PubMed PubMed
- Belatacept and Long-Term Outcomes in Kidney Transplantation.| | PubMed PubMed
- An Update on Calcineurin Inhibitor-Free Regimens: The Need Persists, but the Landscape has Changed.| | PubMed PubMed
- Belatacept and Long-Term Outcomes in Kidney Transplantation.| | PubMed PubMed
- A Prospective Cohort Study of Mineral Metabolism After Kidney Transplantation.| | PubMed PubMed
- A Computational Gene Expression Score for Predicting Immune Injury in Renal Allografts.| | PubMed PubMed
- Evaluation of the effect of tofacitinib exposure on outcomes in kidney transplant patients.| | PubMed PubMed
- The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study.| | PubMed PubMed
- Role of podocyte B7-1 in diabetic nephropathy.| | PubMed PubMed
- Clinical aspects: focusing on key unique organ-specific issues of renal transplantation.| | PubMed PubMed
- Long-term belatacept exposure maintains efficacy and safety at 5 years: results from the long-term extension of the BENEFIT study.| | PubMed PubMed
- Tofacitinib in kidney transplantation.| | PubMed PubMed
- Report of the second joint meeting of ESOT and AST: current pipelines in biotech and pharma.| | PubMed PubMed
- Native renal function after combined liver-kidney transplant for type 1 hepatorenal syndrome: initial report on the use of postoperative Technetium-99 m-mercaptoacetyltriglycine scans.| | PubMed PubMed
- Ciprofloxacin prophylaxis in kidney transplant recipients reduces BK virus infection at 3 months but not at 1 year.| | PubMed PubMed
- Belatacept in kidney transplantation.| | PubMed PubMed
- Polyomavirus BK replication in de novo kidney transplant patients receiving tacrolimus or cyclosporine: a prospective, randomized, multicenter study.| | PubMed PubMed
- Belatacept for prevention of acute rejection in adult patients who have had a kidney transplant: an update.| | PubMed PubMed
- Altered balance between effector T cells and FOXP3+ HELIOS+ regulatory T cells after thymoglobulin induction in kidney transplant recipients.| | PubMed PubMed
- Improvement in renal function in kidney transplant recipients switched from cyclosporine or tacrolimus to belatacept: 2-year results from the long-term extension of a phase II study.| | PubMed PubMed
- Randomized phase 2b trial of tofacitinib (CP-690,550) in de novo kidney transplant patients: efficacy, renal function and safety at 1 year.| | PubMed PubMed
- Are calcineurin inhibitors-free regimens ready for prime time?| | PubMed PubMed
- Beyond belatacept: praise and progress for the FDA.| | PubMed PubMed
- Targeting JAK3 in kidney transplantation: current status and future options.| | PubMed PubMed
- C4d/CD34 double-immunofluorescence staining of renal allograft biopsies for assessing peritubular capillary C4d positivity.| | PubMed PubMed
- Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients.| | PubMed PubMed
- Belatacept-versus cyclosporine-based immunosuppression in renal transplant recipients with pre-existing diabetes.| | PubMed PubMed
- Belatacept.| | PubMed PubMed
- Challenges and opportunities in targeting the costimulation pathway in solid organ transplantation.| | PubMed PubMed
- Novel strategies in immunosuppression: issues in perspective.| | PubMed PubMed
- Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies).| | PubMed PubMed
- Sotrastaurin, a novel small molecule inhibiting protein-kinase C: randomized phase II study in renal transplant recipients.| | PubMed PubMed
- A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis.| | PubMed PubMed
- Response to questions regarding the design and results of the IMPACT trial.| | PubMed PubMed
- An integrated safety profile analysis of belatacept in kidney transplant recipients.| | PubMed PubMed
- Belatacept-based regimens versus a cyclosporine A-based regimen in kidney transplant recipients: 2-year results from the BENEFIT and BENEFIT-EXT studies.| | PubMed PubMed
- Extended valganciclovir prophylaxis in D+/R- kidney transplant recipients is associated with long-term reduction in cytomegalovirus disease: two-year results of the IMPACT study.| | PubMed PubMed
- Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade.| | PubMed PubMed
- How the development of new biological agents may help minimize immunosuppression in kidney transplantation: the impact of belatacept.| | PubMed PubMed
- Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients.| | PubMed PubMed
- Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study.| | PubMed PubMed
- Associations of pretransplant diabetes mellitus, new-onset diabetes after transplant, and acute rejection with transplant outcomes: an analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) database.| | PubMed PubMed
- Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.| | PubMed PubMed
- Five-year safety and efficacy of belatacept in renal transplantation.| | PubMed PubMed
- The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients.| | PubMed PubMed
- A phase III study of belatacept versus cyclosporine in kidney transplants from extended criteria donors (BENEFIT-EXT study).| | PubMed PubMed
- A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).| | PubMed PubMed
- Kidney transplantation at UCSF: 8,300 transplants and onward.| | PubMed PubMed
- Novel B cell therapeutic targets in transplantation and immune-mediated glomerular diseases.| | PubMed PubMed
- KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary.| | PubMed PubMed
- Calcineurin-inhibitor-free immunosuppression based on the JAK inhibitor CP-690,550: a pilot study in de novo kidney allograft recipients.| | PubMed PubMed
- Kidney transplantation: the ideal immunosuppression regimen.| | PubMed PubMed
- Transplantation: To convert or not to convert: lessons from the CONVERT trial.| | PubMed PubMed
- The AST's perspective on the proposed kidney allocation system.| | PubMed PubMed
- The challenge of achieving target drug concentrations in clinical trials: experience from the Symphony study.| | PubMed PubMed
- Long-term renal function and cardiovascular disease risk in obese kidney donors.| | PubMed PubMed
- Evolving trends in induction therapy.| | PubMed PubMed
- Assessment of belatacept-mediated costimulation blockade through evaluation of CD80/86-receptor saturation.| | PubMed PubMed
- Mycophenolic acid exposure after administration of mycophenolate mofetil in the presence and absence of cyclosporin in renal transplant recipients.| | PubMed PubMed
- The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation.| | PubMed PubMed
- What's next in the pipeline.| | PubMed PubMed
- Tolerance versus immunosuppression: a perspective.| | PubMed PubMed
- Association of four DNA polymorphisms with acute rejection after kidney transplantation.| | PubMed PubMed
- Open letter to the FDA: new drug trials must be relevant.| | PubMed PubMed
- A randomized, multicenter study of steroid avoidance, early steroid withdrawal or standard steroid therapy in kidney transplant recipients.| | PubMed PubMed
- Costimulation blockade in autoimmunity and transplantation.| | PubMed PubMed
- Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: The CAESAR Study. Am J Transplant 7, 560-570, 2007.| | PubMed PubMed
- Proteomics of plasma and urine in primary nephrotic syndrome in children.| | PubMed PubMed
- Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus. Am J Transplant 7 1506-1514, 2007.| | PubMed PubMed
- Rituximab failed to improve nephrotic syndrome in renal transplant patients with recurrent focal segmental glomerulosclerosis.| | PubMed PubMed
- A phase I/II randomized open-label multicenter trial of efalizumab, a humanized anti-CD11a, anti-LFA-1 in renal transplantation.| | PubMed PubMed
- Novel immunosuppression: small molecules and biologics.| | PubMed PubMed
- Pharmacokinetics, safety, and efficacy of mycophenolate mofetil in combination with sirolimus or ciclosporin in renal transplant patients.| | PubMed PubMed
- Costimulation blockade--what will the future bring?| | PubMed PubMed
- Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus.| | PubMed PubMed
- Sirolimus: defining nephrotoxicity in the renal transplant recipient.| | PubMed PubMed
- Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin.| | PubMed PubMed
- Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: the CAESAR Study.| | PubMed PubMed
- T cell costimulation: a rational target in the therapeutic armamentarium for autoimmune diseases and transplantation.| | PubMed PubMed
- Therapeutic drug monitoring of mycophenolic acid in solid organ transplant patients treated with mycophenolate mofetil: review of the literature.| | PubMed PubMed
- Living donor kidney transplant recipients and clinical trials: participation profiles and impact on post-transplant care.| | PubMed PubMed
- Immunosuppression: today, tomorrow, and withdrawal.| | PubMed PubMed
- Interleukin-2 receptor antagonist induction in modern immunosuppression regimens for renal transplant recipients.| | PubMed PubMed
- Antibodies come back to the forefront in transplantation.| | PubMed PubMed
- A multicenter, prospective study of C2-monitored cyclosporine microemulsion in a U.S. population of de novo renal transplant recipients.| | PubMed PubMed
- Toxicity-sparing protocols using mycophenolate mofetil in renal transplantation.| | PubMed PubMed
- Current use and future trends in induction therapy.| | PubMed PubMed
- Rapidly developing nephrocalcinosis in a patient with end-stage liver disease who received a domino liver transplant from a patient with known congenital oxalosis.| | PubMed PubMed
- Costimulation blockade with belatacept in renal transplantation.| | PubMed PubMed
- A drug of the past, a lesson for the future.| | PubMed PubMed
- Guidelines for the treatment and management of new-onset diabetes after transplantation.| | PubMed PubMed
- New insights into the pathogenesis and the therapy of recurrent focal glomerulosclerosis.| | PubMed PubMed
- Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation.| | PubMed PubMed
- An open-label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency.| | PubMed PubMed
- Rationale and design of the DIRECT study: a comparative assessment of the hyperglycemic effects of tacrolimus and cyclosporine following renal transplantation.| | PubMed PubMed
- A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus.| | PubMed PubMed
- Chronic induction. What's new in the pipeline.| | PubMed PubMed
- BK nephropathy in kidney transplant recipients treated with a calcineurin inhibitor-free immunosuppression regimen.| | PubMed PubMed
- Interleukin-2 receptor antagonists and aggressive steroid minimization strategies for kidney transplant patients.| | PubMed PubMed
- Infliximab in the treatment of steroid-dependent ulcerative colitis.| | PubMed PubMed
- A decade of progress in kidney transplantation.| | PubMed PubMed
- Recurrent focal glomerulosclerosis in the era of genetics of podocyte proteins: theory and therapy.| | PubMed PubMed
- Optimizing the use of cyclosporine (Neoral) for recipients of living donor kidneys.| | PubMed PubMed
- Retransplantation in patients with graft loss caused by polyoma virus nephropathy.| | PubMed PubMed
- Pharmacokinetics of daclizumab and mycophenolate mofetil with cyclosporine and steroids in renal transplantation.| | PubMed PubMed
- CD69 expression on peripheral CD8 T cells correlates with acute rejection in renal transplant recipients.| | PubMed PubMed
- Immunosuppression minimization: current and future trends in transplant immunosuppression.| | PubMed PubMed
- Prevalence and management of anemia in renal transplant recipients: a European survey.| | PubMed PubMed
- De novo use of sirolimus in immunosuppression regimens in kidney and kidney-pancreas transplantation at the University of California, San Francisco.| | PubMed PubMed
- Multicenter randomized prospective trial of steroid withdrawal in renal transplant recipients receiving basiliximab, cyclosporine microemulsion and mycophenolate mofetil.| | PubMed PubMed
- New monoclonal antibodies in renal transplantation.| | PubMed PubMed
- Pharmacokinetic and pharmacodynamic studies of one or two doses of daclizumab in renal transplantation.| | PubMed PubMed
- What's in the pipeline? New immunosuppressive drugs in transplantation.| | PubMed PubMed
- A long-term comparison of tacrolimus (FK506) and cyclosporine in kidney transplantation: evidence for improved allograft survival at five years.| | PubMed PubMed
- Effect of calcineurin inhibitor therapy on P-gp expression and function in lymphocytes of renal transplant patients: a preliminary evaluation.| | PubMed PubMed
- Interleukin-2 receptor monoclonal antibodies in renal transplantation: current use and emerging regimens.| | PubMed PubMed
- Results of 3-year phase III clinical trials with daclizumab prophylaxis for prevention of acute rejection after renal transplantation.| | PubMed PubMed
- Daclizumab (humanized anti-IL2Ralpha mAb) prophylaxis for prevention of acute rejection in renal transplant recipients with delayed graft function.| | PubMed PubMed
- Is complete avoidance of calcineurin inhibitors or steroids now possible? Importance of patient selection and choice of regimen.| | PubMed PubMed
- Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation.| | PubMed PubMed
- Rapid steroid withdrawal versus standard steroid therapy in patients treated with basiliximab, cyclosporine, and mycophenolate mofetil for the prevention of acute rejection in renal transplantation.| | PubMed PubMed
- Tacrolimus (FK 506) in kidney transplantation: five-year survival results of the U.S. multicenter, randomized, comparative trial.| | PubMed PubMed
- The role of newer monoclonal antibodies in renal transplantation.| | PubMed PubMed
- Phase I trial of HuM291, a humanized anti-CD3 antibody, in patients receiving renal allografts from living donors.| | PubMed PubMed
- A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.| | PubMed PubMed
- Coadministration of tacrolimus and mycophenolate mofetil in stable kidney transplant patients: pharmacokinetics and tolerability.| | PubMed PubMed
- The role of daclizumab in balancing resources for inpatient and outpatient transplant services.| | PubMed PubMed
- Daclizumab prevents acute rejection and improves patient survival post transplantation: 1 year pooled analysis.| | PubMed PubMed
- Recurrent and de novo glomerular disease after renal transplantation: a report from Renal Allograft Disease Registry (RADR).| | PubMed PubMed
- Daclizumab: novel biologic immunoprophylaxis for prevention of acute rejection in renal transplantation.| | PubMed PubMed
- Potential of daclizumab in solid organ transplantation.| | PubMed PubMed
- Can antibody prophylaxis allow sparing of other immunosuppressives?| | PubMed PubMed
- Recurrent and de novo glomerular disease after renal transplantation: a report from renal allograft disease registry.| | PubMed PubMed
- Review of transplantation--1999.| | PubMed PubMed
- Histopathologic findings from 2-year protocol biopsies from a U.S. multicenter kidney transplant trial comparing tarolimus versus cyclosporine: a report of the FK506 Kidney Transplant Study Group.| | PubMed PubMed
- Daclizumab: outcome of phase III trials and mechanism of action. Double Therapy and the Triple Therapy Study Groups.| | PubMed PubMed
- Single-center long-term results of renal transplantation for IgA nephropathy.| | PubMed PubMed
- Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation. Daclizumab Triple Therapy Study Group.| | PubMed PubMed
- Selection strategies for successful utilization of less than 15.kg pediatric donor kidneys.| | PubMed PubMed
- Anaesthetic management of children with type II and III Gaucher disease.| | PubMed PubMed
- A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression after cadaveric renal transplantation. FK506 Kidney Transplant Study Group.| | PubMed PubMed
- FK 506 in kidney transplantation: results of the U.S.A. randomized comparative phase III study. The FK 506 Kidney Transplant Study Group.| | PubMed PubMed
- Immunologic and patient selection strategies for successful utilization of less than 15 kg pediatric donor kidneys--long term experiences with 40 transplants.| | PubMed PubMed
- A phase I trial of humanized anti-interleukin 2 receptor antibody in renal transplantation.| | PubMed PubMed
- An open-label, concentration-ranging trial of FK506 in primary kidney transplantation: a report of the United States Multicenter FK506 Kidney Transplant Group.| | PubMed PubMed
- A multicenter trial of FK506 (tacrolimus) therapy in refractory acute renal allograft rejection. A report of the Tacrolimus Kidney Transplantation Rescue Study Group.| | PubMed PubMed
- One-year follow-up of an open-label trial of FK506 for primary kidney transplantation. A report of the U.S. Multicenter FK506 Kidney Transplant Group.| | PubMed PubMed
- Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis.| | PubMed PubMed
- In vivo (phase I) trial and in vitro efficacy of humanized anti-Tac for the prevention of rejection in renal transplant recipients.| | PubMed PubMed
- Pentoxifylline does not prevent the cytokine-induced first dose reaction following OKT3--a randomized, double-blind placebo-controlled study.| | PubMed PubMed
- Fibrosing cholestatic hepatitis in renal transplant recipients.| | PubMed PubMed
- Histopathological concordance of paired renal allograft biopsy cores. Effect on the diagnosis and management of acute rejection.| | PubMed PubMed
- Long-term outcome in kidney transplant patients with hepatitis C (HCV) infection.| | PubMed PubMed
- Phase II FK 506 multicenter concentration control study: one-year follow-up.| | PubMed PubMed
- The risk of transmission of hepatitis B from HBsAg(-), HBcAb(+), HBIgM(-) organ donors.| | PubMed PubMed
- Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis.| | PubMed PubMed
- Pentoxifylline reduces the first-dose reactions following OKT3.| | PubMed PubMed
- Nontransmission of hepatitis C from cadaver kidney donors to transplant recipients.| | PubMed PubMed
- Hepatitis C--its prevalence in end-stage renal failure patients and clinical course after kidney transplantation.| | PubMed PubMed
- Recurrent focal glomerulosclerosis: natural history and response to therapy.| | PubMed PubMed
- Cytokine and T cell receptor gene expression at the site of allograft rejection.| | PubMed PubMed
- Hepatitis C virus in cadaver organ donors: prevalence and risk of transmission to transplant recipients.| | PubMed PubMed
- Effect of cyclosporine on the clinical course of HBsAg-positive renal transplant patients.| | PubMed PubMed
- Improved results with combined donor-specific transfusion (DST) and sequential therapy protocol.| | PubMed PubMed
- Inability of cyclosporine to completely prevent the recurrence of focal glomerulosclerosis after kidney transplantation.| | PubMed PubMed
- Immunologic alterations induced by donor-specific transfusion.| | PubMed PubMed
- Successful management of the highly sensitized renal allograft recipient.| | PubMed PubMed
- The incidence and impact of herpes simplex virus infections in the first month following renal transplantation.| | PubMed PubMed
- Cyclosporine provides better success rates for both higher- and lower-risk cadaveric kidney transplant recipients.| | PubMed PubMed
- How to improve results for second renal allografts.| | PubMed PubMed
- Is cyclosporine effective in preventing recurrence of immune-mediated glomerular disease after renal transplantation?| | PubMed PubMed
- Posttransplant renal rejection: comparison of quantitative scintigraphy, US, and MR imaging.| | PubMed PubMed
- Donor-specific blood transfusions versus cyclosporine--the DST story.| | PubMed PubMed
- Has cyclosporine really relegated pretransplant blood transfusions to therapeutic obsolescence?| | PubMed PubMed
- Observations relating to the incidence of the acquired immune deficiency syndrome and other possibly associated conditions in a large population of renal transplant recipients.| | PubMed PubMed
- Sonography in the diagnosis of acute renal allograft rejection and cyclosporine nephrotoxicity.| | PubMed PubMed
- The beneficial effect of pretransplant blood transfusions in cyclosporine-treated cadaver renal allograft recipients.| | PubMed PubMed
- Renal allograft rejection: US evaluation.| | PubMed PubMed
- The clinical course of IgA-nephropathy and Henoch-Schönlein purpura following renal transplantation.| | PubMed PubMed
- Clinical management of immunosuppressive therapy for cyclosporine-treated recipients of cadaver kidney transplants at one to six months.| | PubMed PubMed
- Is a "low" dose of prednisone better than a "high" dose at the time of renal transplantation?| | PubMed PubMed
- A seven-year experience with donor-specific blood transfusions. Results and considerations for maximum efficacy.| | PubMed PubMed
- Pharmacokinetics of sulfisoxazole in renal transplant patients.| | PubMed PubMed
- Dramatic improvement in the success rate for renal transplants in diabetic recipients with donor-specific transfusions.| | PubMed PubMed
- Peptic ulcer disease in kidney transplant recipients.| | PubMed PubMed
- Parathyroid and bone response of the diabetic patient to uremia.| | PubMed PubMed
- Long-term renal function in kidney donors. Sustained compensatory hyperfiltration with no adverse effects.| | PubMed PubMed
- The role of blood transfusions in renal transplantation.| | PubMed PubMed
- De novo and recurrent membranous glomerulopathy following kidney transplantation.| | PubMed PubMed
- Furosemide assays and disposition in healthy volunteers and renal transplant patients.| | PubMed PubMed
- Urinary kallikrein excretion after renal transplantation: relationship to hypertension, graft source, and renal function.| | PubMed PubMed
- Blood transfusions before and on the day of transplantation: effects on cadaver graft survival.| | PubMed PubMed
- Update of the University of California at San Francisco experience with donor-specific blood transfusions.| | PubMed PubMed
- Blood transfusions and kidney transplantation.| | PubMed PubMed
- Prednisone and prednisolone bioavailability in renal transplant patients.| | PubMed PubMed
- Prognostic features of early renal transplant rejections.| | PubMed PubMed
- Septic arthritis following renal transplantation.| | PubMed PubMed
- An alternative to cadaver kidney transplants for patients with insulin-dependent diabetes mellitus.| | PubMed PubMed
- Incidence, characteristics, and outcome of recipients sensitized after donor-specific blood transfusions.| | PubMed PubMed
- Improved graft survival following donor-specific blood transfusions.| | PubMed PubMed
- Prevention of prednisone-induced negative nitrogen balance. Effect of dietary modification on urea generation rate in patients on hemodialysis receiving high-dose glucocorticoids.| | PubMed PubMed
- 1,500 renal transplants at one center: evolution of a strategy for optimal success.| | PubMed PubMed
- Furosemide kinetics and dynamics after kidney transplant.| | PubMed PubMed
- Recurrent systemic lupus erythematosus involving renal allografts.| | PubMed PubMed
- Decreased secondary hyperparathyroidism in diabetic patients receiving hemodialysis.| | PubMed PubMed
- Graft survival with high levels of cytotoxic antibodies.| | PubMed PubMed
- Improved graft survival with donor-specific transfusion pretreatment.| | PubMed PubMed
- Pretreatment with donor-specific blood transfusions in related recipients with high MLC.| | PubMed PubMed
- Prednisolone disposition in cushingoid and noncushingoid kidney transplant patients.| | PubMed PubMed
- Improved outcome following renal transplantation with reduction in the immunosuppression therapy for rejection episodes.| | PubMed PubMed
- The role of hypertension in hemodialysis-associated atherosclerosis.| | PubMed PubMed
- Post-transplantation pyelonephritis: factors producing low patient and transplant morbidity.| | PubMed PubMed
- Deliberate donor-specific blood transfusions prior to living related renal transplantation. A new approach.| | PubMed PubMed
- The organization of a successful donor-specific transfusion protocol in related recipients with high MLC.| | PubMed PubMed
- Donor-specific blood transfusions in HLA-D-disparate one-haplotype-related allografts.| | PubMed PubMed
- Results and significance of angiography in potential kidney donors.| | PubMed PubMed
- The transplanted kidney as a source of hepatitis B infection.| | PubMed PubMed
- Analysis of costs and outcomes of renal transplantation at one center. Its implications.| | PubMed PubMed
- Comparative study of albumin solution and cryoprecipitated plasma for renal preservation: a preliminary report.| | PubMed PubMed
- HLA-D antigen disparity and HLA-DRw antibodies in intrafamilial renal allograft survival.| | PubMed PubMed
- The influence of donor age on graft survival.| | PubMed PubMed
- Do blood transfusions enhance the possibility of a compatible transplant?| | PubMed PubMed
- Pretransplant cytotoxic antibodies do not segregate kidney transplant recipients into responder and non-responder groups.| | PubMed PubMed
- Immunologic factors determining survival of cadaver-kidney transplants. The effect of HLA serotyping, cytotoxic antibodies and blood transfusions on graft survival.| | PubMed PubMed
- Leukocyte migration inhibitory factor (LIF) as an indicator of presensitization and allograft survival.| | PubMed PubMed
- A ten year experience with cadaver kidney preservation using cryoprecipitated plasma.| | PubMed PubMed
- Cadaver kidney transplantation provided from one center within a large geographical region.| | PubMed PubMed
- The effect of hypothermic pulsatile perfusion on glomerular epithelial surface structures studied by scanning electron microscopy.| | PubMed PubMed
- Hepatitis-B reactivation after renal transplantation.| | PubMed PubMed
- Renal transplantation in systemic lupus erythematosus.| | PubMed PubMed
- Renal vein renin in hypertension. Diagnostic and therapeutic implications.| | PubMed PubMed
- Tumorous hyperparathyroidism in hypophosphatemic vitamin D--resistant rickets.| | PubMed PubMed
 
    