Biography
I have been at UCSF since 1975 and on the faculty of the Department of Medicine in the division of Nephrology since 1976 and have been involved with the transplant service in patient care and clinical trials with novel immunosuppression drugs
Education
Institution | Degree | Dept or School | End Date |
---|---|---|---|
University of California, San Francisco | Residency | School of Medicine |
Board Certifications
American Board of Internal Medicine, Internal Medicine
American Board of Internal Medicine, Nephrology - Subspecialty
Clinical Expertise
Internal Medicine
Transplant Nephrology
Kidney Transplantation
Pancreas Transplantation
Living Kidney Donor Transplantation
End Stage Renal Disease (Kidney Failure)
Chronic Kidney Disease
Clinical Trials
- Daratumumab and Belatacept for Desensitization (NCT04827979)Related Conditions: Kidney Transplant, Transplants| Start Date: | End Date:
In the News
January, 28, 2016 | UCSF Transplant Surgery
August, 27, 2014 | UCSF Transplant Surgery
Grants and Funding
- Applying precision MEdicine to optimize desensitization with noveL bIOlogics or cellular theRApies in highly sensiTized kidney transplant patiEnts (AMELIORATE) | NIH | 2014-07-01 - 2024-05-31 | Role: Principal Investigator
- General Clinical Research Center | NIH | 1974-12-01 - 2009-03-31 | Role: Co-Investigator
Research Interests
Transplant Nephrology
Publications
MOST RECENT PUBLICATIONS FROM A TOTAL OF 286
- Antiplasma cell antibodies: A new era of human leukocyte antigen antibody control in solid organ transplantation.| | PubMed
- Anti-HLA serologic response to CD38-targeting desensitization therapy is challenged by peripheral memory B cells in highly sensitized kidney transplant candidates.| | PubMed
- Poised for Innovation: Considerations for End Points for New Drug Development in Kidney Transplantation.| | PubMed
- Long-term Safety in Epstein-Barr Virus-Seropositive Kidney-only Transplant Recipients Treated With Belatacept in Clinical Practice: Final Study Results From the ENLiST Registry.| | PubMed
- The hepatocyte growth factor mimetic, ANG-3777, in kidney transplant recipients with delayed graft function: Results from a randomized phase 3 trial.| | PubMed
- Isatuximab Monotherapy for Desensitization in Highly Sensitized Patients Awaiting Kidney Transplant.| | PubMed
- State of the art in childhood nephrotic syndrome: concrete discoveries and unmet needs.| | PubMed
- Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients: A Randomized Clinical Trial.| | PubMed
- Understanding heterogeneity of human bone marrow plasma cell maturation and survival pathways by single-cell analyses.| | PubMed
- Open letter to Bristol Myers Squibb: Belatacept; we aren't done yet.| | PubMed
- Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study.| | PubMed
- Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.| | PubMed
- Human Bone Marrow Plasma Cell Atlas: Maturation and Survival Pathways Unraveled by Single Cell Analyses.| | PubMed
- Burden of neutropenia and leukopenia among adult kidney transplant recipients: A systematic literature review of observational studies.| | PubMed
- Obinutuzumab Effectively Depletes Key B-cell Subsets in Blood and Tissue in End-stage Renal Disease Patients.| | PubMed
- Infliximab Induction Lacks Efficacy and Increases BK Virus Infection in Deceased Donor Kidney Transplant Recipients: Results of the CTOT-19 Trial.| | PubMed
- Outcomes among CMV-mismatched and highly sensitized kidney transplants recipients who develop neutropenia.| | PubMed
- IL-6 and TNFα Drive Extensive Proliferation of Human Tregs Without Compromising Their Lineage Stability or Function.| | PubMed
- Conversion from Calcineurin Inhibitor- to Belatacept-Based Maintenance Immunosuppression in Renal Transplant Recipients: A Randomized Phase 3b Trial.| | PubMed
- Application of the iBox prognostication system as a surrogate endpoint in the TRANSFORM randomised controlled trial: proof-of-concept study.| | PubMed
- Tests for the noninvasive diagnosis of kidney transplant rejection should be evaluated by kidney transplant programs.| | PubMed
- A Comparison of Ex Vivo Expanded Human Regulatory T Cells Using Allogeneic Stimulated B Cells or Monocyte-Derived Dendritic Cells.| | PubMed
- Interleukin-6 blockade with tocilizumab increases Tregs and reduces T effector cytokines in renal graft inflammation: A randomized controlled trial.| | PubMed
- Single-Cell RNA Sequencing of Tocilizumab-Treated Peripheral Blood Mononuclear Cells as an in vitro Model of Inflammation.| | PubMed
- Optimization of de novo belatacept-based immunosuppression administered to renal transplant recipients.| | PubMed
- Phase 3 trial Design of the Hepatocyte Growth Factor Mimetic ANG-3777 in Renal Transplant Recipients With Delayed Graft Function.| | PubMed
- The impact of belatacept on the phenotypic heterogeneity of renal T cell-mediated alloimmune response: The critical role of maintenance treatment and inflammatory load.| | PubMed
- Single-cell RNA sequencing of Tocilizumab-treated peripheral blood mononuclear cells as an in vitro model of inflammation.| | PubMed
- A urine score for noninvasive accurate diagnosis and prediction of kidney transplant rejection.| | PubMed
- Further Evidence That the Soluble Urokinase Plasminogen Activator Receptor Does Not Directly Injure Mice or Human Podocytes.| | PubMed
- Assessment of 19 Genes and Validation of CRM Gene Panel for Quantitative Transcriptional Analysis of Molecular Rejection and Inflammation in Archival Kidney Transplant Biopsies.| | PubMed
- A randomized, phase 1b study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of bleselumab, a fully human, anti-CD40 monoclonal antibody, in kidney transplantation.| | PubMed
- Evidence-based practice: Guidance for using everolimus in combination with low-exposure calcineurin inhibitors as initial immunosuppression in kidney transplant patients.| | PubMed
- Safety, pharmacokinetics, and pharmacodynamic activity of obinutuzumab, a type 2 anti-CD20 monoclonal antibody for the desensitization of candidates for renal transplant.| | PubMed
- Two-year outcomes in de novo renal transplant recipients receiving everolimus-facilitated calcineurin inhibitor reduction regimen from the TRANSFORM study.| | PubMed
- Characterizing pre-transplant and post-transplant kidney rejection risk by B cell immune repertoire sequencing.| | PubMed
- Identifying a potential biomarker for primary focal segmental glomerulosclerosis and its association with recurrence after transplantation.| | PubMed
- Efficacy and Safety of a Tofacitinib-based Immunosuppressive Regimen After Kidney Transplantation: Results From a Long-term Extension Trial.| | PubMed
- Nuclear Factor of Activated T Cell-regulated Cytokine Gene Expression for Adjustment of Tacrolimus in Kidney Transplant Recipients: A Randomized Controlled Pilot Trial.| | PubMed
- A randomized, phase 2 study of ASP0113, a DNA-based vaccine, for the prevention of CMV in CMV-seronegative kidney transplant recipients receiving a kidney from a CMV-seropositive donor.| | PubMed
- Everolimus with Reduced Calcineurin Inhibitor Exposure in Renal Transplantation.| | PubMed
- Outcomes at 7 years post-transplant in black vs nonblack kidney transplant recipients administered belatacept or cyclosporine in BENEFIT and BENEFIT-EXT.| | PubMed
- Targeted Transcriptional Profiling of Kidney Transplant Biopsies.| | PubMed
- Mycophenolate Mofetil Withdrawal With Conversion to Everolimus to Treat BK Virus Infection in Kidney Transplant Recipients.| | PubMed
- Ten-year outcomes in a randomized phase II study of kidney transplant recipients administered belatacept 4-weekly or 8-weekly.| | PubMed
- Polyclonal Regulatory T Cell Therapy for Control of Inflammation in Kidney Transplants.| | PubMed
- Retrospective evaluation of the efficacy and safety of belatacept with thymoglobulin induction and maintenance everolimus: A single-center clinical experience.| | PubMed
- Transplant trials with Tregs: perils and promises.| | PubMed
- B Cell Receptor Genes Associated With Tolerance Identify a Cohort of Immunosuppressed Patients With Improved Renal Allograft Graft Function.| | PubMed
- A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis.| | PubMed
- Belatacept: the challenges with transformational drugs.| | PubMed
- Early post-transplant conversion from tacrolimus to belatacept for prolonged delayed graft function improves renal function in kidney transplant recipients.| | PubMed
- Safety and Efficacy Outcomes 3 Years After Switching to Belatacept From a Calcineurin Inhibitor in Kidney Transplant Recipients: Results From a Phase 2 Randomized Trial.| | PubMed
- Current status of costimulatory blockade in renal transplantation.| | PubMed
- Costimulatory Blockade and Use of mTOR Inhibitors: Avoiding Injury Part 2.| | PubMed
- Steroid-Responsive Acute Rejection Should Not Be the End Point for Immunosuppressive Trials.| | PubMed
- Belatacept and Long-Term Outcomes in Kidney Transplantation.| | PubMed
- An Update on Calcineurin Inhibitor-Free Regimens: The Need Persists, but the Landscape has Changed.| | PubMed
- Belatacept and Long-Term Outcomes in Kidney Transplantation.| | PubMed
- A Prospective Cohort Study of Mineral Metabolism After Kidney Transplantation.| | PubMed
- A Computational Gene Expression Score for Predicting Immune Injury in Renal Allografts.| | PubMed
- Evaluation of the effect of tofacitinib exposure on outcomes in kidney transplant patients.| | PubMed
- The kSORT assay to detect renal transplant patients at high risk for acute rejection: results of the multicenter AART study.| | PubMed
- Role of podocyte B7-1 in diabetic nephropathy.| | PubMed
- Clinical aspects: focusing on key unique organ-specific issues of renal transplantation.| | PubMed
- Long-term belatacept exposure maintains efficacy and safety at 5 years: results from the long-term extension of the BENEFIT study.| | PubMed
- Tofacitinib in kidney transplantation.| | PubMed
- Report of the second joint meeting of ESOT and AST: current pipelines in biotech and pharma.| | PubMed
- Native renal function after combined liver-kidney transplant for type 1 hepatorenal syndrome: initial report on the use of postoperative Technetium-99 m-mercaptoacetyltriglycine scans.| | PubMed
- Ciprofloxacin prophylaxis in kidney transplant recipients reduces BK virus infection at 3 months but not at 1 year.| | PubMed
- Belatacept in kidney transplantation.| | PubMed
- Polyomavirus BK replication in de novo kidney transplant patients receiving tacrolimus or cyclosporine: a prospective, randomized, multicenter study.| | PubMed
- Belatacept for prevention of acute rejection in adult patients who have had a kidney transplant: an update.| | PubMed
- Altered balance between effector T cells and FOXP3+ HELIOS+ regulatory T cells after thymoglobulin induction in kidney transplant recipients.| | PubMed
- Improvement in renal function in kidney transplant recipients switched from cyclosporine or tacrolimus to belatacept: 2-year results from the long-term extension of a phase II study.| | PubMed
- Randomized phase 2b trial of tofacitinib (CP-690,550) in de novo kidney transplant patients: efficacy, renal function and safety at 1 year.| | PubMed
- Are calcineurin inhibitors-free regimens ready for prime time?| | PubMed
- Beyond belatacept: praise and progress for the FDA.| | PubMed
- Targeting JAK3 in kidney transplantation: current status and future options.| | PubMed
- C4d/CD34 double-immunofluorescence staining of renal allograft biopsies for assessing peritubular capillary C4d positivity.| | PubMed
- Three-year outcomes from BENEFIT, a randomized, active-controlled, parallel-group study in adult kidney transplant recipients.| | PubMed
- Belatacept-versus cyclosporine-based immunosuppression in renal transplant recipients with pre-existing diabetes.| | PubMed
- Belatacept.| | PubMed
- Challenges and opportunities in targeting the costimulation pathway in solid organ transplantation.| | PubMed
- Novel strategies in immunosuppression: issues in perspective.| | PubMed
- Belatacept-based regimens are associated with improved cardiovascular and metabolic risk factors compared with cyclosporine in kidney transplant recipients (BENEFIT and BENEFIT-EXT studies).| | PubMed
- Sotrastaurin, a novel small molecule inhibiting protein-kinase C: randomized phase II study in renal transplant recipients.| | PubMed
- A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis.| | PubMed
- Response to questions regarding the design and results of the IMPACT trial.| | PubMed
- An integrated safety profile analysis of belatacept in kidney transplant recipients.| | PubMed
- Belatacept-based regimens versus a cyclosporine A-based regimen in kidney transplant recipients: 2-year results from the BENEFIT and BENEFIT-EXT studies.| | PubMed
- Extended valganciclovir prophylaxis in D+/R- kidney transplant recipients is associated with long-term reduction in cytomegalovirus disease: two-year results of the IMPACT study.| | PubMed
- Islet transplantation in type 1 diabetic patients using calcineurin inhibitor-free immunosuppressive protocols based on T-cell adhesion or costimulation blockade.| | PubMed
- How the development of new biological agents may help minimize immunosuppression in kidney transplantation: the impact of belatacept.| | PubMed
- Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients.| | PubMed
- Switching from calcineurin inhibitor-based regimens to a belatacept-based regimen in renal transplant recipients: a randomized phase II study.| | PubMed
- Associations of pretransplant diabetes mellitus, new-onset diabetes after transplant, and acute rejection with transplant outcomes: an analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) database.| | PubMed
- Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab.| | PubMed
- Five-year safety and efficacy of belatacept in renal transplantation.| | PubMed
- The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients.| | PubMed
- A phase III study of belatacept versus cyclosporine in kidney transplants from extended criteria donors (BENEFIT-EXT study).| | PubMed
- A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study).| | PubMed
- Kidney transplantation at UCSF: 8,300 transplants and onward.| | PubMed
- Novel B cell therapeutic targets in transplantation and immune-mediated glomerular diseases.| | PubMed
- KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary.| | PubMed
- Calcineurin-inhibitor-free immunosuppression based on the JAK inhibitor CP-690,550: a pilot study in de novo kidney allograft recipients.| | PubMed
- Kidney transplantation: the ideal immunosuppression regimen.| | PubMed
- Transplantation: To convert or not to convert: lessons from the CONVERT trial.| | PubMed
- The AST's perspective on the proposed kidney allocation system.| | PubMed
- The challenge of achieving target drug concentrations in clinical trials: experience from the Symphony study.| | PubMed
- Long-term renal function and cardiovascular disease risk in obese kidney donors.| | PubMed
- Evolving trends in induction therapy.| | PubMed
- Assessment of belatacept-mediated costimulation blockade through evaluation of CD80/86-receptor saturation.| | PubMed
- Mycophenolic acid exposure after administration of mycophenolate mofetil in the presence and absence of cyclosporin in renal transplant recipients.| | PubMed
- The effect of costimulatory and interleukin 2 receptor blockade on regulatory T cells in renal transplantation.| | PubMed
- What's next in the pipeline.| | PubMed
- Tolerance versus immunosuppression: a perspective.| | PubMed
- Association of four DNA polymorphisms with acute rejection after kidney transplantation.| | PubMed
- Open letter to the FDA: new drug trials must be relevant.| | PubMed
- A randomized, multicenter study of steroid avoidance, early steroid withdrawal or standard steroid therapy in kidney transplant recipients.| | PubMed
- Costimulation blockade in autoimmunity and transplantation.| | PubMed
- Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: The CAESAR Study. Am J Transplant 7, 560-570, 2007.| | PubMed
- Proteomics of plasma and urine in primary nephrotic syndrome in children.| | PubMed
- Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus. Am J Transplant 7 1506-1514, 2007.| | PubMed
- Rituximab failed to improve nephrotic syndrome in renal transplant patients with recurrent focal segmental glomerulosclerosis.| | PubMed
- A phase I/II randomized open-label multicenter trial of efalizumab, a humanized anti-CD11a, anti-LFA-1 in renal transplantation.| | PubMed
- Novel immunosuppression: small molecules and biologics.| | PubMed
- Pharmacokinetics, safety, and efficacy of mycophenolate mofetil in combination with sirolimus or ciclosporin in renal transplant patients.| | PubMed
- Costimulation blockade--what will the future bring?| | PubMed
- Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus.| | PubMed
- Sirolimus: defining nephrotoxicity in the renal transplant recipient.| | PubMed
- Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin.| | PubMed
- Cyclosporine sparing with mycophenolate mofetil, daclizumab and corticosteroids in renal allograft recipients: the CAESAR Study.| | PubMed
- T cell costimulation: a rational target in the therapeutic armamentarium for autoimmune diseases and transplantation.| | PubMed
- Therapeutic drug monitoring of mycophenolic acid in solid organ transplant patients treated with mycophenolate mofetil: review of the literature.| | PubMed
- Living donor kidney transplant recipients and clinical trials: participation profiles and impact on post-transplant care.| | PubMed
- Immunosuppression: today, tomorrow, and withdrawal.| | PubMed
- Interleukin-2 receptor antagonist induction in modern immunosuppression regimens for renal transplant recipients.| | PubMed
- Antibodies come back to the forefront in transplantation.| | PubMed
- A multicenter, prospective study of C2-monitored cyclosporine microemulsion in a U.S. population of de novo renal transplant recipients.| | PubMed
- Toxicity-sparing protocols using mycophenolate mofetil in renal transplantation.| | PubMed
- Current use and future trends in induction therapy.| | PubMed
- Rapidly developing nephrocalcinosis in a patient with end-stage liver disease who received a domino liver transplant from a patient with known congenital oxalosis.| | PubMed
- Costimulation blockade with belatacept in renal transplantation.| | PubMed
- A drug of the past, a lesson for the future.| | PubMed
- Guidelines for the treatment and management of new-onset diabetes after transplantation.| | PubMed
- New insights into the pathogenesis and the therapy of recurrent focal glomerulosclerosis.| | PubMed
- Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation.| | PubMed
- An open-label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency.| | PubMed
- Rationale and design of the DIRECT study: a comparative assessment of the hyperglycemic effects of tacrolimus and cyclosporine following renal transplantation.| | PubMed
- A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus.| | PubMed
- Chronic induction. What's new in the pipeline.| | PubMed
- BK nephropathy in kidney transplant recipients treated with a calcineurin inhibitor-free immunosuppression regimen.| | PubMed
- Interleukin-2 receptor antagonists and aggressive steroid minimization strategies for kidney transplant patients.| | PubMed
- Infliximab in the treatment of steroid-dependent ulcerative colitis.| | PubMed
- A decade of progress in kidney transplantation.| | PubMed
- Recurrent focal glomerulosclerosis in the era of genetics of podocyte proteins: theory and therapy.| | PubMed
- Optimizing the use of cyclosporine (Neoral) for recipients of living donor kidneys.| | PubMed
- Retransplantation in patients with graft loss caused by polyoma virus nephropathy.| | PubMed
- Pharmacokinetics of daclizumab and mycophenolate mofetil with cyclosporine and steroids in renal transplantation.| | PubMed
- CD69 expression on peripheral CD8 T cells correlates with acute rejection in renal transplant recipients.| | PubMed
- Immunosuppression minimization: current and future trends in transplant immunosuppression.| | PubMed
- Prevalence and management of anemia in renal transplant recipients: a European survey.| | PubMed
- De novo use of sirolimus in immunosuppression regimens in kidney and kidney-pancreas transplantation at the University of California, San Francisco.| | PubMed
- Multicenter randomized prospective trial of steroid withdrawal in renal transplant recipients receiving basiliximab, cyclosporine microemulsion and mycophenolate mofetil.| | PubMed
- New monoclonal antibodies in renal transplantation.| | PubMed
- Pharmacokinetic and pharmacodynamic studies of one or two doses of daclizumab in renal transplantation.| | PubMed
- What's in the pipeline? New immunosuppressive drugs in transplantation.| | PubMed
- A long-term comparison of tacrolimus (FK506) and cyclosporine in kidney transplantation: evidence for improved allograft survival at five years.| | PubMed
- Effect of calcineurin inhibitor therapy on P-gp expression and function in lymphocytes of renal transplant patients: a preliminary evaluation.| | PubMed
- Interleukin-2 receptor monoclonal antibodies in renal transplantation: current use and emerging regimens.| | PubMed
- Results of 3-year phase III clinical trials with daclizumab prophylaxis for prevention of acute rejection after renal transplantation.| | PubMed
- Daclizumab (humanized anti-IL2Ralpha mAb) prophylaxis for prevention of acute rejection in renal transplant recipients with delayed graft function.| | PubMed
- Is complete avoidance of calcineurin inhibitors or steroids now possible? Importance of patient selection and choice of regimen.| | PubMed
- Multicenter trial exploring calcineurin inhibitors avoidance in renal transplantation.| | PubMed
- Rapid steroid withdrawal versus standard steroid therapy in patients treated with basiliximab, cyclosporine, and mycophenolate mofetil for the prevention of acute rejection in renal transplantation.| | PubMed
- Tacrolimus (FK 506) in kidney transplantation: five-year survival results of the U.S. multicenter, randomized, comparative trial.| | PubMed
- The role of newer monoclonal antibodies in renal transplantation.| | PubMed
- Phase I trial of HuM291, a humanized anti-CD3 antibody, in patients receiving renal allografts from living donors.| | PubMed
- A calcineurin inhibitor-sparing regimen with sirolimus, mycophenolate mofetil, and anti-CD25 mAb provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function.| | PubMed
- Coadministration of tacrolimus and mycophenolate mofetil in stable kidney transplant patients: pharmacokinetics and tolerability.| | PubMed
- The role of daclizumab in balancing resources for inpatient and outpatient transplant services.| | PubMed
- Daclizumab prevents acute rejection and improves patient survival post transplantation: 1 year pooled analysis.| | PubMed
- Recurrent and de novo glomerular disease after renal transplantation: a report from Renal Allograft Disease Registry (RADR).| | PubMed
- Daclizumab: novel biologic immunoprophylaxis for prevention of acute rejection in renal transplantation.| | PubMed
- Potential of daclizumab in solid organ transplantation.| | PubMed
- Can antibody prophylaxis allow sparing of other immunosuppressives?| | PubMed
- Recurrent and de novo glomerular disease after renal transplantation: a report from renal allograft disease registry.| | PubMed
- Review of transplantation--1999.| | PubMed
- Histopathologic findings from 2-year protocol biopsies from a U.S. multicenter kidney transplant trial comparing tarolimus versus cyclosporine: a report of the FK506 Kidney Transplant Study Group.| | PubMed
- Daclizumab: outcome of phase III trials and mechanism of action. Double Therapy and the Triple Therapy Study Groups.| | PubMed
- Single-center long-term results of renal transplantation for IgA nephropathy.| | PubMed
- Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation. Daclizumab Triple Therapy Study Group.| | PubMed
- Selection strategies for successful utilization of less than 15.kg pediatric donor kidneys.| | PubMed
- A comparison of tacrolimus (FK506) and cyclosporine for immunosuppression after cadaveric renal transplantation. FK506 Kidney Transplant Study Group.| | PubMed
- FK 506 in kidney transplantation: results of the U.S.A. randomized comparative phase III study. The FK 506 Kidney Transplant Study Group.| | PubMed
- Immunologic and patient selection strategies for successful utilization of less than 15 kg pediatric donor kidneys--long term experiences with 40 transplants.| | PubMed
- A phase I trial of humanized anti-interleukin 2 receptor antibody in renal transplantation.| | PubMed
- An open-label, concentration-ranging trial of FK506 in primary kidney transplantation: a report of the United States Multicenter FK506 Kidney Transplant Group.| | PubMed
- A multicenter trial of FK506 (tacrolimus) therapy in refractory acute renal allograft rejection. A report of the Tacrolimus Kidney Transplantation Rescue Study Group.| | PubMed
- One-year follow-up of an open-label trial of FK506 for primary kidney transplantation. A report of the U.S. Multicenter FK506 Kidney Transplant Group.| | PubMed
- Circulating factor associated with increased glomerular permeability to albumin in recurrent focal segmental glomerulosclerosis.| | PubMed
- In vivo (phase I) trial and in vitro efficacy of humanized anti-Tac for the prevention of rejection in renal transplant recipients.| | PubMed
- Pentoxifylline does not prevent the cytokine-induced first dose reaction following OKT3--a randomized, double-blind placebo-controlled study.| | PubMed
- Fibrosing cholestatic hepatitis in renal transplant recipients.| | PubMed
- Histopathological concordance of paired renal allograft biopsy cores. Effect on the diagnosis and management of acute rejection.| | PubMed
- Long-term outcome in kidney transplant patients with hepatitis C (HCV) infection.| | PubMed
- Phase II FK 506 multicenter concentration control study: one-year follow-up.| | PubMed
- The risk of transmission of hepatitis B from HBsAg(-), HBcAb(+), HBIgM(-) organ donors.| | PubMed
- Plasmapheresis reduces proteinuria and serum capacity to injure glomeruli in patients with recurrent focal glomerulosclerosis.| | PubMed
- Pentoxifylline reduces the first-dose reactions following OKT3.| | PubMed
- Nontransmission of hepatitis C from cadaver kidney donors to transplant recipients.| | PubMed
- Hepatitis C--its prevalence in end-stage renal failure patients and clinical course after kidney transplantation.| | PubMed
- Recurrent focal glomerulosclerosis: natural history and response to therapy.| | PubMed
- Cytokine and T cell receptor gene expression at the site of allograft rejection.| | PubMed
- Hepatitis C virus in cadaver organ donors: prevalence and risk of transmission to transplant recipients.| | PubMed
- Effect of cyclosporine on the clinical course of HBsAg-positive renal transplant patients.| | PubMed
- Improved results with combined donor-specific transfusion (DST) and sequential therapy protocol.| | PubMed
- Inability of cyclosporine to completely prevent the recurrence of focal glomerulosclerosis after kidney transplantation.| | PubMed
- Immunologic alterations induced by donor-specific transfusion.| | PubMed
- Successful management of the highly sensitized renal allograft recipient.| | PubMed
- The incidence and impact of herpes simplex virus infections in the first month following renal transplantation.| | PubMed
- Cyclosporine provides better success rates for both higher- and lower-risk cadaveric kidney transplant recipients.| | PubMed
- How to improve results for second renal allografts.| | PubMed
- Is cyclosporine effective in preventing recurrence of immune-mediated glomerular disease after renal transplantation?| | PubMed
- Posttransplant renal rejection: comparison of quantitative scintigraphy, US, and MR imaging.| | PubMed
- Donor-specific blood transfusions versus cyclosporine--the DST story.| | PubMed
- Has cyclosporine really relegated pretransplant blood transfusions to therapeutic obsolescence?| | PubMed
- Observations relating to the incidence of the acquired immune deficiency syndrome and other possibly associated conditions in a large population of renal transplant recipients.| | PubMed
- Sonography in the diagnosis of acute renal allograft rejection and cyclosporine nephrotoxicity.| | PubMed
- The beneficial effect of pretransplant blood transfusions in cyclosporine-treated cadaver renal allograft recipients.| | PubMed
- Renal allograft rejection: US evaluation.| | PubMed
- The clinical course of IgA-nephropathy and Henoch-Schönlein purpura following renal transplantation.| | PubMed
- Clinical management of immunosuppressive therapy for cyclosporine-treated recipients of cadaver kidney transplants at one to six months.| | PubMed
- Is a "low" dose of prednisone better than a "high" dose at the time of renal transplantation?| | PubMed
- A seven-year experience with donor-specific blood transfusions. Results and considerations for maximum efficacy.| | PubMed
- Pharmacokinetics of sulfisoxazole in renal transplant patients.| | PubMed
- Dramatic improvement in the success rate for renal transplants in diabetic recipients with donor-specific transfusions.| | PubMed
- Peptic ulcer disease in kidney transplant recipients.| | PubMed
- Parathyroid and bone response of the diabetic patient to uremia.| | PubMed
- Long-term renal function in kidney donors. Sustained compensatory hyperfiltration with no adverse effects.| | PubMed
- The role of blood transfusions in renal transplantation.| | PubMed
- De novo and recurrent membranous glomerulopathy following kidney transplantation.| | PubMed
- Furosemide assays and disposition in healthy volunteers and renal transplant patients.| | PubMed
- Urinary kallikrein excretion after renal transplantation: relationship to hypertension, graft source, and renal function.| | PubMed
- Blood transfusions before and on the day of transplantation: effects on cadaver graft survival.| | PubMed
- Update of the University of California at San Francisco experience with donor-specific blood transfusions.| | PubMed
- Blood transfusions and kidney transplantation.| | PubMed
- Prednisone and prednisolone bioavailability in renal transplant patients.| | PubMed
- Prognostic features of early renal transplant rejections.| | PubMed
- Septic arthritis following renal transplantation.| | PubMed
- An alternative to cadaver kidney transplants for patients with insulin-dependent diabetes mellitus.| | PubMed
- Incidence, characteristics, and outcome of recipients sensitized after donor-specific blood transfusions.| | PubMed
- Improved graft survival following donor-specific blood transfusions.| | PubMed
- Prevention of prednisone-induced negative nitrogen balance. Effect of dietary modification on urea generation rate in patients on hemodialysis receiving high-dose glucocorticoids.| | PubMed
- 1,500 renal transplants at one center: evolution of a strategy for optimal success.| | PubMed
- Furosemide kinetics and dynamics after kidney transplant.| | PubMed
- Recurrent systemic lupus erythematosus involving renal allografts.| | PubMed
- Decreased secondary hyperparathyroidism in diabetic patients receiving hemodialysis.| | PubMed
- Graft survival with high levels of cytotoxic antibodies.| | PubMed
- Improved graft survival with donor-specific transfusion pretreatment.| | PubMed
- Pretreatment with donor-specific blood transfusions in related recipients with high MLC.| | PubMed
- Prednisolone disposition in cushingoid and noncushingoid kidney transplant patients.| | PubMed
- Improved outcome following renal transplantation with reduction in the immunosuppression therapy for rejection episodes.| | PubMed
- The role of hypertension in hemodialysis-associated atherosclerosis.| | PubMed
- Post-transplantation pyelonephritis: factors producing low patient and transplant morbidity.| | PubMed
- Deliberate donor-specific blood transfusions prior to living related renal transplantation. A new approach.| | PubMed
- The organization of a successful donor-specific transfusion protocol in related recipients with high MLC.| | PubMed
- Donor-specific blood transfusions in HLA-D-disparate one-haplotype-related allografts.| | PubMed
- Results and significance of angiography in potential kidney donors.| | PubMed
- The transplanted kidney as a source of hepatitis B infection.| | PubMed
- Analysis of costs and outcomes of renal transplantation at one center. Its implications.| | PubMed
- Comparative study of albumin solution and cryoprecipitated plasma for renal preservation: a preliminary report.| | PubMed
- HLA-D antigen disparity and HLA-DRw antibodies in intrafamilial renal allograft survival.| | PubMed
- The influence of donor age on graft survival.| | PubMed
- Do blood transfusions enhance the possibility of a compatible transplant?| | PubMed
- Pretransplant cytotoxic antibodies do not segregate kidney transplant recipients into responder and non-responder groups.| | PubMed
- Immunologic factors determining survival of cadaver-kidney transplants. The effect of HLA serotyping, cytotoxic antibodies and blood transfusions on graft survival.| | PubMed
- Leukocyte migration inhibitory factor (LIF) as an indicator of presensitization and allograft survival.| | PubMed
- A ten year experience with cadaver kidney preservation using cryoprecipitated plasma.| | PubMed
- Cadaver kidney transplantation provided from one center within a large geographical region.| | PubMed
- The effect of hypothermic pulsatile perfusion on glomerular epithelial surface structures studied by scanning electron microscopy.| | PubMed
- Hepatitis-B reactivation after renal transplantation.| | PubMed
- Renal transplantation in systemic lupus erythematosus.| | PubMed
- Renal vein renin in hypertension. Diagnostic and therapeutic implications.| | PubMed
- Tumorous hyperparathyroidism in hypophosphatemic vitamin D--resistant rickets.| | PubMed